According to the Phyton 27 News newsletter, some growers have reported potential negative interactions between Phyton 27 and B-Nine. Burns were reported by a grower when using the same spray tank for separate applications. Even washing the tank thoroughly seems not helping. Crop sensitivity is different with Kalanchoes been more sensitive to this mix. "Do not tank mix B-Nine with copper-containing products and do not apply B-Nine withing 7 days before of after application of such products as burning of leaves may result."